The live-action film Cells at Work ! is making waves at the Japanese box office. Its creator, Akane Shimizu, posted a photo celebrating the film's 6.2 billion yen in sales.
Impressive milestone: Over 6 billion yen after 75 days of launch
Holding the No. 1 spot at the box office for four consecutive weeks, the live-action film Cells at Work! officially reached a domestic gross of 6 billion yen on February 13. After just 13 days, this figure continued to increase to 6.2 billion yen (equivalent to 41.49 million USD) with over 4.6 million tickets sold. This is a remarkable achievement, helping the film to be included in the list of highest-grossing Japanese films of all time.

The author celebrates success with commemorative paintings
To mark this resounding success, author Akane Shimizu posted a special illustration on the series' official X (formerly Twitter) account. In the illustration, characters such as Red Blood Cells, White Blood Cells, and Platelets appear humorously, expressing the author's joy and gratitude to the fans.

🔴 #映画はたらく細胞⚪️
— 映画『はたらく細胞』公式 (@saibou_movie) February 27, 2025
⋱㊗️興収6⃣2⃣億円突破🎊⋰
原作者・清水茜先生( @yellow_flame_ )から、赤血球・白血球・血小板揃い踏みの描き下ろしイラスト到着📦
「映画はたらく細胞が多くの方に楽しんでいただけて、とても嬉しいです!応援してくださる皆様に心から感謝申し上げます!」… pic.twitter.com/28rc9lA9fC
The author also sent thanks to the audience through the post:
"I'm so happy that so many people love Cells at Work! I would like to sincerely thank everyone who supported this work!"
The painting received an enthusiastic response from fans, with thousands of likes and shares. From manga to live-action, it has affirmed the strong influence of the work on the community of Japanese culture lovers.
Surpassing many other famous works
With this impressive revenue, Cells at Work! has become the 54th highest-grossing Japanese film in the history of Japanese cinema. Notably, the film has surpassed Thermae Romae - Mari Yamazaki's famous live-action work in 2012. This is also the highest-grossing film in director Hideki Takeuchi's career up to now.
Trailer Cells at Work! live action.
What makes Cells at Work! attractive is firstly the impressive setting of the world inside the human body, then the perfect combination of science and entertainment. The characters are built vividly and closely, helping the audience learn medical knowledge while enjoying emotional moments of entertainment.
Content and the future of Cells at Work!
Cells at Work! is a Japanese manga series written by Akane Shimizu. The story is set inside a human body, where approximately 37 trillion cells work together to sustain life. The two main characters are Red Blood Cell, a clumsy but hard-working girl whose job is to transport oxygen to the tissues and bring CO2 back to the lungs, and White Blood Cell, a warrior who specializes in destroying invading bacteria and viruses.

There are also many other cells with specific roles: cute Platelets that help blood clot, powerful Killer T Cells that fight threats, elegant but ruthless Macrophages that destroy invaders, or tragic Cancer Cells with their own stories.
Through each episode, viewers witness cells facing "enemies" such as bacteria, flu viruses, cancer cells, or even everyday situations such as scratches, pollen allergies, heatstroke... through dramatic, humorous and easy-to-understand details.

The special thing about Cells at Work! is the combination of science and entertainment. Rather than dry scientific knowledge, the series helps the audience understand their bodies better through close storytelling. From the small battles of cells to health messages, the work cleverly conveys the meaning that every cell, no matter how small, is a silent hero that helps protect our lives. If you want to learn and relax at the same time, this is definitely a great choice!
With huge box office success, Cells at Work! has created a real fever in the Japanese cinema industry and left a deep impression in the hearts of fans. Let's wait for the next updates about this famous work with Hobiverse!